Lab on chip refers to technologies which allow operations which normally require a laboratory -synthesis and analysis of chemicals – on a very miniaturized scale, within a portable or handheld device.
Benefits of lab on chip include:
- Analysis of samples at a place exactly where the samples are generated
- Easier to control the movement and interaction of samples, making reactions much more efficient, and reducing chemical waste.
The main challenge to development of lab-on-a-chip devices is the design and fabrication of devices on a very small scale which are functional and cost-effective.
Integrated micro fluid technology for Mass spectrometer:
Recently innovated Lab on chip based technology equipped with cutting edge advanced integrated micro fluidic technology to prepare, separate and electro spray biological samples directly into traditional mass spectrometers (MS). This process speeds up mass spectrometry to reduce time & error in material analysis by taking small volumes of sample. It takes just 3 minutes while a typical chromatography process takes 30 minutes. It effectively enables the analysis various analyses like urine, blood, plasma, protein, antibodies etc.
Printable micro fluid based reusable chip that reduces cost of clinical diagnostics to just $0.01 along with its complexity. Its production takes 20 minutes and it can be cheaply available in developing nation.
This chip platform is effective in performing various functions like cellular manipulation, single cell rupture and cell isolation. It shows impressive results specific analytical separation of biological material, concentration and characterization. The device keeps the electronic circuit isolated from the micro fluid chips. Thus lengthen the lifetime of device and can be reuse also.
This innovative technology intends to improve to revamp drug development. This fascinating technology consists of organ chip, software and instrumental system. The company already started fabricating chips to mimic human lung, liver, intestine and skin, thus give privilege to user to conduct experiments in their lab without requiring experts. Pharmaceutical industries and researchers can test their drugs on chip. This is done by keeping living human cells in controlled environment i.e. maintain continuous fluid flow, cyclic breathing and peristalsis. Every chip consists of hollow channels lines by thousands of cells and tissues, thus recreating micro-environment of human body.